“backsplicing”的音标：
英式：/ˌbækˈslaɪsɪŋ/
美式：/ˌbækˈslaɪsɪŋ/
“backsplicing”的用法和例句8句：
- Backsplicing is a non-canonical RNA splicing mechanism that generates circular RNAs (circRNAs) by joining the 3' end of a transcript to its 5' end.
- Circular RNAs produced via backsplicing are often more stable than linear RNAs due to their lack of free ends.
- The backsplicing process is facilitated by complementary sequences, such as inverted repeats, in the pre-mRNA.
- Aberrant backsplicing events have been implicated in various diseases, including cancer and neurodegenerative disorders.
- Researchers use specialized bioinformatics tools to identify and quantify backsplicing events from RNA sequencing data.
- Backsplicing can be regulated by RNA-binding proteins that promote or inhibit the circularization of specific exons.
- Unlike canonical splicing, which removes introns to form linear mRNAs, backsplicing bypasses the typical 5' to 3' splicing order.
- The discovery of backsplicing has expanded our understanding of RNA complexity and its roles in gene expression regulation.
以上参考资料是词义通为您整理的单词“backsplicing”的解释和含义，如有错漏请向我们提供反馈意见。
来源：词义通 | 更新时间：2026-11-06 15:01:28 | 如有错漏欢迎反馈纠错
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